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Pharmacist's Real Life Experience
a pharmacist/pharmacy manager at Walgreens and fed up with how neurologists
have treated me and others that I visit with at the counter.
You are completely right about Topamax on your web page.
One neurologist at the Headache Clinic had me taking 400mg of Topamax, along
with about eight other prescriptions. None of them worked, and my neurologist
acted like I was crazy when I told her!
And imagine trying to work as a pharmacist on all that crap!!...Especially
the Topamax. That stuff made it impossible to speak, think or function. Add to
that a bunch of other horrible medicines prescribed by neurologists and you have
yourself one hot mess!!!!
I did my research and found your Migraine
Defense product (thank God!!). As
a pharmacist, I was never big on natural medications but it has really helped.
Thank you so much for all that you do for migraineurs!!
Topamax is the most widely prescribed migraine prophylactic drug available.
It is also the leading migraine drug with the most known damaging
Are the Risks and Low Efficacy Worth It to You?
Considering Topamax is covered by many insurance plans and prescribed by doctors,
most people who hold a prescription will have it filled without first learning
about the implications and risks of taking this drug and not know how they may
be affected by the known side effects.
Is insurance paying for your migraine drugs?
No matter what you currently think you know about Topamax, for your sake and
that of your loved ones, you should read this important message to help you make a knowledgeable decision about what you take for migraine prevention.
Taking Topamax (topiramate) is a Choice
all know how devastating migraines can be and how they often interrupt life.
You may find yourself in a desperate situation where you are willing to take
any risk for the slim chance that your migraines will end or at least be reduce
to a tolerable number.
Anti-seizure mediations such as Topamax have been tried for many years as
a last resort in hopes that they may work on the brain to at least make
a person unaware that a migraine is occurring. Today we know that through extensive
marketing campaigns to doctors and patients, many doctors, perhaps not even aware
of the risks or history of the drug, often prescribe Topamax to patients whom
they see for the first time.
It should important for you to know when making a decision to try Topamax
or stay on it that the drug has not changed, only the marketing campaign changed
- the risks are still the same.
Click here to
learn more about safe migraine prevention.
Your Brain On
Topamax works to alter the chemistry of your brain. Topamax work in an
area called the temporal lobes which are apart from the actual migraine center.
Altering brain chemicals in these areas can cause changes in a person's personality,
his or her ability to think, make decisions, remember words and names, learn
new things, and speak correctly. The higher the dosage, the more likelihood that
these problems will occur.
According to reports submitted to the FDA, the functions most
likely to be impaired include:
• short term memory (ability to learn new things, store information,
and recall events)
• attention (staying focused)
• concentration (thinking clearly)
formation (saying the right words)
• and organization of thoughts (what to do next and what is the
answer to a question).
down" has been used as an appropriate term to describe the effect Topamax
has on a person.
You Get Migraines and What Stops Them
Side effects stopped the trials.
Topamax trials were abruptly stopped by the manufacturer
side effects became all too obvious to ignore or explain away.
By stopping their own trials, a pharmaceutical company can legally avoid
providing full disclosure of side effects to the FDA because the results
of the trial do not become part of the overall product report submitted to the
Topamax Publication (7517114 02T566 © OMN 2005) lists only the most common
adverse events that may occur while taking Topamax (see side bar).
About the Safe Way to Prevent Migraines
Safe for Children?
FDA Warnings Say NO!
Topamax is approved only for adult migraine patients.
your child has been prescribed Topamax for migraines, please pay close attention
to the warnings about Topamax. Learn all you can about how your child could be
handicapped by side effects that may cause a disruption in his or her ability
to learn. Topamax is not approved for anyone under the age of 18.
There are good reasons why Topamax is only for adults.
Learn what is safe
for migraine prevention for
Can Start at an Early Age
How Well Does Topamax
Work for Migraines?
Works About 35% of the Time According to Topamax's Own Research
certainly works for some of the people some of the time. The results of a
trial of 1,700 people who suffered an average of 5.5 migraines per month showed
at the end of a six month period that by
using 200 mg of Topamax a day the average person could expect to reduce
the number of migraines by just two per month.
"The primary end point [the end of six months
of continued use to determine the effect] of the pivotal trials was changed from
a baseline in mean monthly migraine frequency. TOPAMAX 50 mg BID (100 mg/day)
effectively reduced migraines by 2.1 attacks per month from a baseline of approximately
5.5 migraines per month in both studies vs 0.8 and 11 with placebo." from Topamax
It is recommended to doctors that a patient take Topamax for six months
with increases in the dosage to a point that may reach a level of 400 mg per
day by the end of that time in order to see if Topamax will work an average
37% of the time in preventing a patient's migraines.
In contrast, Migraine Defense can show excellent results in four to six weeks.
Type of Migraine May Determine Best Remedy
Topamax is Over-Prescribed
Topamax marketing campaigns directed at doctors and other
advertisements directed at patients has been the number one reason for its increase
in use. During the last several years, the makers
of Topamax have paid millions of dollars to settle government fines for misrepresenting
What is Triggering Your Migraines
Now Do What is Best for
At this point you may be asking, "Now that I know more about Topamax,
what is the best thing to do to prevent my migraines?"
If you want to be free of migraines, without the worry of what damage Topamax
may be doing to your mind and body, click here.
If you have any questions about migraines, call 1-866-367-5953 or
Just Say No To Topamax
Get started today with your risk-free trial pack of Tuliv
Migraine Defense containing a full six weeks supply and
everything you need to get you on your way to a migraine-free life.
Note: Since Tuliv Migraine Defense can be taken along
there is no need to wait - you can start today.
Here to learn more about this offer
• or call
Migraines - What Doctors Don't Tell You
Testimonies from Real People
Ingredients in Migraine Defense
Migraine Safe Supplements
Migraine Research Report
Why Hormones Cause
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Notice: The information on this web site is provided as general
health information and may not be applicable to your particular health condition.
Medical diagnoses and treatments may be properly addressed by your professional
healthcare provider. Tuliv Ltd. Co. shall not be liable for the contents, products,
errors or omissions in the information provided, or advice obtained from this
web site, written documents, emails, phone conversation, or orders. Tuliv Migraine
Defense and other products sold under the name Tuliv or Christian Body are sold
as a dietary supplement under the regulations of the FDA. The statements made
on this web site, in written correspondence, or verbal conversations have not
been evaluated by the FDA. The statements contained herein have not been evaluated
by the FDA. This product is not intended to diagnose, treat, cure or prevent
any disease. Tuliv does not provide medical advice and information provided should
not be used as medical advice.
Topamax® is a registered trademark of Ortho-McNeil Neurologics, Inc
Tuliv® and Migraine Defense® are
registered trademarks of Tuliv Ltd. Co.
Copyright ® 2004-2010 Tuliv Ltd. Co. All rights reserved.
Topamax Side Effects
Facts About Side Effects:
Drug companies can and do stop trials that reveal side effects in order
to avoid reporting them to the FDA when making application for drug approval.
These side effects are later released as "postmarketing
For example, personality
disorder (a major deviation from normal patterns of behavior) is listed
as a postmarketing side effect of Topamax (topiramate) that has a high probability
of occurring frequently, see The
SIDER Side Effect Resource for a complete list of more than 180 different
reported side effects.
Why risk the side effects when you have a safe alternative?
Cognitive/Neuropsychiatric Adverse Events Adverse
events most often associated with the use of TOPAMAX® were related to the
central nervous system and were observed in both the epilepsy and migraine populations.
Cognitive Related Dysfunction (e.g. confusion, psychomotor slowing, difficulty with concentration and attention, difficulty with memory, speech, or language problems, particularly word finding difficulties).
Psychiatric Behavioral Disturbances (e.g. depression or mood problems)
Somnolence and Fatigue (e.g. drowsiness, sleepy, tired)
Kidney Stones: An explanation for the association of TOPAMAX® and kidney stones may lie in the fact that topiramate is a carbonic anhydrase inhibitor.
FDA Instructions for Doctors:
Patients should be warned about the potential for somnolence, dizziness, confusion,
and difficulty concentrating and advised not to drive or operate machinery.
Reporting Topamax Side Effects:
You may report side effects
to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).
Side Effects and Warning From Topamax's FDA Required Prescribing
TOPAMAX® is approved for migraine prevention in adults only.
FDA Reported Side Effects
Numbness and tingling
This is known as paresthesia and is the most common side effect of TOPAMAX. People
have described this as numbness or "pins and needles," most often in
the arms or legs.
Some people may feel tired while taking TOPAMAX. More people reported fatigue
during the early stage of treatment.
Some people may have weight loss while taking TOPAMAX. This seems to be related
to the dose of TOPAMAX taken.
Difficulty with concentration attention and difficulty with memory
TOPAMAX may make it hard to concentrate. Some people may have memory recall issues.
This reaction varies, but people have described it as "difficulty finding
the right word" or "losing my train of thought."
Other common TOPAMAX side effects are loss of appetite, nausea, diarrhea,
and taste change.
Warnings and Precautions
TOPAMAX® may cause eye problems. Serious eye problems include: sudden
decrease in vision with or without eye pain and redness; blockage of fluid in
the eye causing increased pressure in the eye (secondary angle closure glaucoma).
These eye problems can lead to permanent loss of vision if not treated. You should
call your healthcare professional right away if you have any new eye symptoms.
TOPAMAX® may cause decreased sweating and increased body temperature (fever).
People, especially children, should be watched for signs of decreased sweating
and fever, especially in hot temperatures. Some people may need to be
hospitalized for this condition.
TOPAMAX® may cause suicidal thoughts or actions. Pay attention
to any changes and call your doctor right away if you have any of these symptoms,
especially if they are new, worse, or worry you: thoughts about suicide or dying,
attempts to commit suicide, new or worse depression, new or worse anxiety,
feeling agitated or restless, panic attacks, trouble sleeping (insomnia),
new or worse irritability,
acting aggressive, being angry or violent, acting on dangerous impulses,
an extreme increase in activity and talking (mania), or other unusual changes
in behavior or mood.
Serious risks associated with TOPAMAX® include lowered bicarbonate levels
in the blood resulting in an increase in the acidity of the blood (metabolic
acidosis). Symptoms could include hyperventilation (rapid, deep breathing), tiredness,
loss of appetite, irregular heartbeat, or changes in the level of alertness.
Chronic, untreated metabolic acidosis may increase
the risk for kidney stones or bone disease.
TOPAMAX® may affect how you think, and cause confusion, problems
with concentration, attention, memory, or speech, depression or mood problems,
tiredness, and sleepiness.
Do not stop taking TOPAMAX® without first talking to your doctor. Stopping
TOPAMAX® suddenly can cause serious problems.
TOPAMAX® may cause high blood ammonia levels. High ammonia in the blood can
affect your mental activities, slow your alertness, make you feel tired, or cause
The most common side effects of TOPAMAX® include: tingling in arms and legs,
loss of appetite, nausea, taste change, diarrhea, weight loss, nervousness, and
upper respiratory tract infection.
These are not all the possible side effects of TOPAMAX
®. For more information,
ask your healthcare professional or pharmacist.
Use in Specific Populations
Tell your doctor if you are pregnant or plan to become pregnant. It is not known
if TOPAMAX® will harm your unborn baby. There may be an association between
the use of TOPAMAX® during pregnancy and birth defects or low birth weight.
full U.S. Prescribing Information and Medication Guide.
Food and Drug Administration (FDA) Government Report on Topamax.
FDA Warning Update: Mar 4, 2011
"New data suggest that the drug Topamax (topiramate)
and its generic versions increase the risk for the birth defects cleft lip and
cleft palate in babies born to women using the drug when they become pregnant
or use the medication during pregnancy," the U.S.
Food and Drug Administration said today.
“Health care professionals should carefully consider the benefits and risks
of topiramate when prescribing it to women of childbearing age,” said Russell
Katz, M.D., director of the Division of Neurology Products in the FDA’s
Center for Drug Evaluation and Research. Alternatives should be considered.
NOTE: Please forward this warning to anyone you know is taking Topamax.
See Full FDA Report at www.FDA.gov
from Physicians Desk Reference
Topamax can depress the central nervous system. Be extremely cautious about combining it with alcohol, sedatives, tranquilizers, and other central nervous system depressants.
More common side effects may include:
anxiety, hallucinations, headache, hearing difficulties, hot flashes, impotence,
increased sweating, irritable
bladder, joint pain, kidney stones, low
sex drive, mood swings, confusion, depression,
difficulty with memory, menstrual
problems, mood problems, personality
problems, double vision, drowsiness, fatigue, language
problems, speech problems,
tingling or burning sensations, tremors, weakness, weight loss.
Being prescribed a drug doesn't make it safe for you to take.
If you want performance in a safe migraine preventive without side
effects, then try Tuliv Migraine Defense.
2004, Migraine Defense has been providing all-natural migraine prevention
for men, women, and children.
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