Researching Migraines

The following is an excerpt from an article by Lyle Henry about his Migraine Research Project.

The cause of migraines has either eluded or been ignored by the pharmaceutical world in their search for profitable products. Make no mistake about it, pharmaceuticals are in business for profit rather than to discover cures. The new discoveries are being made by non-profit and/or private independent research that has different goals and motivation.

Personally I had but one goal, to find a way to bring an end to the 43 years of migraine suffering that my wife Eileen was enduring. In order to reach that goal I knew I must apply new research methods to a problem that was as old as recorded history. Having spent nearly 30 years developing a analytical methodology, I felt confident that my method of research would provide a new view of migraines and bring about new discoveries that may produce the solution to migraine prevention.

After discovering the relationship between the hormone secretions of the endocrine system and the occurrence of migraines, I was introduced to Dr. Coleman, a Neuroendocrinologist from Harvard Medical Research, who provided guidance in the development of the anti-migraine (preventive) formula that stopped Eileen’s continuous migraine cycle and brought a complete end to her four decades of migraine suffering.  Since February 2004, Eileen has never had another migraine.

Men, women, and children are now migraine-free because of this research and the creation of Tuliv Migraine Defense formula that was designed to work on the biological cause of migraines rather than drugging the brain.

What I Discovered

Three things became clear: 1. migraine is a condition resulting from the inherited genetic makeup of the DNA in a person. making him or her predisposed to the migraine syndrome, 2. the migraine syndrome is stimulated by how hormonal secretions of the glands of the endocrine system react on the hormone receptor proteins of specific cells in the body, 3. when activated these cells produce chemicals that ignite a reaction in the trigeminal vascular systems that result in the pain associated with a migraine.

These are the very reasons why men and women, both children and adults, get migraine headaches. A migraine can be “triggered” by a variety of things, but the “gun” is loaded at birth and “the bullet is powdered” by the hormones of the body.

Ultimately my research focused on the relationship between the hormone secretions from the pituitary gland and the resulting occurrence of migraines. I don’t want to get too far into the science of this other than to let you know the pituitary gland controls many life stages and cyclical events of the body, including growth hormones, hormones to start puberty, a women’s monthly menstrual cycle, and even puts us into menopause (yes, I do also mean men).

As you can see, most of these events coincide with migraine occurrences which, as most women already know, demonstrate that migraines are related to hormone changes or fluctuations in the body. Although these changes are controlled by the pituitary gland, it does not mean there is anything wrong with the gland itself. The gland is not the problem or even the cause; it is simply doing what it is designed to do.

The migraine syndrome is dependent on an inherited gene. In virtually every true migraine case that I have studied, I have found a family connection and 95 percent of these were on the maternal side.

As I mentioned, the pituitary gland is not the problem. The hormones secreted by this gland are used as messengers by specialized cells in our bodies to control the production of other hormones. The messengers are let into cells or rejected by proteins that sit on the cells called hormone-receptors. The migraine problem starts within these cells. From these findings I came to the conclusion that the best way to control and manage migraines would be to find a natural solution that manages the cause of the migraines.

In other words, by stopping the roof from leaking it keeps the carpet from being hurt.

The Migraine Cycle

In order to understand the process of migraines, you first need to realize that you get migraines because of a particular gene you inherited. It is that gene that affects the way your body manages hormone fluctuations. Although this is easier to see in the case of women, it holds true for men as well.

After years of research that included the combined work of hundreds of researchers from universities and research hospitals around the world, we* created the Migraine Occurrence Model (MOM).

It was this model that helped map the path to our discovery of how migraines could be prevented. We had long suspected  that in order to get migraines a person must inherit a gene in the DNA from the maternal side of the family. This gene, methylenetetrahydrofolate reductase gene (MTHFR) variant C677T, has been identified as the one that influences susceptibility to migraines.

This gene is found in the mitochondria of specific hormone-producing cells that receive their "production orders" from the pituitary gland by way of hormone-receptors located on the membranes of these cells.. These orders come in the form of protein hormones called glycoproteins. For example, luteinizing hormone (LH), and follicle-stimulating hormone (FSH) instruct cells to produce either progesterone, estrogen, or testosterone.

Problem. It is within the cells in which the MTHFR genes are located that the migraine problem begins. These cells can cause an adverse neurochemical to be released into the blood stream.

This neurochemical is what causes the dilation of the blood vessels in the trigeminovascular system that makes the head hurt). Since the trigeminal nerve is located on both sides of the head and extends likewise behind the eyes and into the face, the pain seem to move around in the head. When pain is felt behind the eyes or as sinus pressure, migraines are often misdiagnosed as sinus headaches and even wrongly treated as sinus infections.

Pain. As the blood vessels intertwined with the nerve endings begin to dilate and swell, the inner-lining of the vessel begins to ooze a chemical through the thin vessel walls. This chemical actually stimulates the nerve endings to secrete powerful blood vessel dilators that turn on a violent chain reaction that continues to apply throbbing pressure on the nerve endings that is felt as the painful lightening-like pinching of a migraine headache.

Relief. Triptans, such as Imitrex, constrict (shrink) these dilated blood vessels to relieve the pressure and abort the migraine. These drugs are designed to stop the pain, but do nothing to prevent the return of another migraine.

Since anti-convulsive and other drugs prescribed for migraines work solely within the brain, it becomes apparent as to why they often fail to prevent migraines when one considers the cause of the migraine problem is not within the brain. One can imagine these drugs as masking the migraines rather than actually preventing them from occurring.

At this point it should become apparent that in order to effectively control migraines and keep them from starting, the solution must address the true nature of the migraine problem rather than altering the brain chemistry with drugs.

Perhaps this can be illustrated best by thinking of the use of drugs to prevent migraines is like throwing a blanket over a burning fire - it may only keep you from realizing that the fire is still burning. You can think of Tuliv Migraine Defense as preventing the matches from being lit. No matches, no fire, no headache.

Tuliv Migraine Defense is the only anti-migraine product that builds a natural defense system in your body to keep you from getting migraines. The source of the problem is where it is designed to work to keep a migraine from being ignited.

Migraine Defense neither adds to nor depletes the body of any hormones. The purpose of Migraine Defense is to manage the problem that causes migraines. Therefore, Migraine Defense is safe for use by men, women, and children*.

Neck Tension Migraines. Migraines are very taxing on the body. Neck muscles and joints become tense, sore, and strained. This pain and tension are often misdiagnosed as the cause, rather than the result of migraines.

Hormone Replacement Therapy. Many women have been prescribed or use hormone replacement therapy, such as estrogen and progesterone, in attempts to control migraines or block the symptoms of menopause. These remedies for migraines are generally short-lived as the body readjusts to the added hormones and this can actually and painfully result in an increase in migraine frequency and intensity. Unfortunately the connection between adding hormones and increased migraines is not understood by most doctors or patients; therefore, HRT continues unchallenged.

Now you know the problem and the solution. You have the right to choose what is best for you. Choose the solution that protects you from migraines. Choose Tuliv Migraine Defense.

Call and visit with a migraine specialist at 1-866-367-5953 (outside the US and Canada call 405-692-4395). You are directly connected to a migraine specialist, without sales pressure or automated operators. All calls are considered personal and confidential. There is no cost or obligation for your call.

Send Emails to Questions@Tuliv.com .